• Hot Saucerman@lemmy.ml
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    1 year ago

    I think allergy suffers already have known this for years… The stuff that works is locked up because it can be used to make meth…

    • dublet@lemmy.world
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      1 year ago

      Yes, it’s pseudoephedrine that you want. Somewhat ironic that Sudafed got its brandname from it, but you can’t easily get the original version anymore.

      Edited: corrected for availibility of the Sudafed - thanks Blue and Cubby.

    • some_guy@lemmy.sdf.org
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      1 year ago

      A frustrating outcome. I used to buy 14 day packs of allergy meds and sometimes didn’t qualify to buy more two or even four days after I ran out. I don’t know what aspect of their restrictions allow this to happen, but it’s bullshit. Also, good luck if you’re going overseas for a month and need a full supply. I believe a doc can prescribe a larger supply, but I shouldn’t have to pay more money and time for a doc appointment to get that.

      • BOMBS@lemmy.world
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        1 year ago

        One thing I’ve realized about US healthcare is that it would rather restrict meds from those that need them than to give access to those that would abuse it.

        • HorseWithNoName@lemm.ee
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          1 year ago

          That’s definitely what they’ve done with opioids. You could have your bone sticking out of your arm and they’d call you a drug addict for being surprised when they give you a motrin.

    • x4740N@lemmy.world
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      1 year ago

      Any backyard chemsit can make meth if they are skilled enough

      Nile Red likely has the capability of doing that

  • starman2112@sh.itjust.works
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    1 year ago

    Representatives for the Consumer Healthcare Products Association, a group that represents OTC drug manufacturers, did not offer any new evidence to counter the FDA’s claims that the drug is ineffective during their presentation Monday.

    The group instead said that if oral phenylephrine were not available over the counter, it would be a significant burden to consumers.

    But it doesn’t work! Consumers are literally using something that’s no better than the naturopathic bullshit found in the next aisle over!

    MAN I hate corporate lobbyists. Outright lying to try and save face.

  • sssm@lemmy.world
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    1 year ago

    Super interestingly, in clinical trials it is less effective than the placebo.

    • Astroturfed@lemmy.world
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      1 year ago

      Yes. I have a few months a year where I have to get some type of decongestant and the most cost effective is generic Pseudoephedrine. It works. My mother bought me phenylephrine a few times when I was younger and it just didn’t do anything. Not surprised about this article one bit.

  • TheAmishMan@lemmy.world
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    1 year ago

    I graduated pharmacy school 8 years ago. This was a thing that was taught in school. This is why you should talk to your pharmacist. Guaifenisin is another ‘garbage drug’ that does virtually nothing; just drink more water

    • kmkz_ninja@lemmy.world
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      1 year ago

      Guaifenisin seems to clear my chest congestion up pretty quickly. If I’m placeboing myself, then lalalala I’m not listening.

    • dantheclamman@lemmy.worldOP
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      1 year ago

      omg are you serious? I always felt like sudafed PE didn’t do much but I thought mucinex helped a bunch with sinus congestion. now I’m here not sure if anything is real.

      Edit for those interested: “extended-release guaifenesin was found to have no effect on all 3 patient-related outcome markers analyzed as measured by the Daily Cough and Phlegm Diary, Spontaneous Symptom Severity Assessment score, and the Wisconsin Upper Respiratory Symptom Survey.”

      Edit again with more: “The greatest effects of treatment with guaifenesin/pseudoephedrine were observed for nasal congestion and sinus headache. Time to overall relief was shorter with guaifenesin/pseudoephedrine (P = 0.038). Significantly more patients reported “the medication was helping during the day” on Day 2 with guaifenesin/pseudoephedrine (P = 0.002). Patient assessments of symptom relief showed a significant preference for guaifenesin/pseudoephedrine versus placebo”

    • PetDinosaurs@lemmy.world
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      1 year ago

      I’m with the others. Guaifenisin seems to work pretty well. Even on it’s own. And I’m a major skeptic.

      Not as well as pseudoephedrine or ibuprofen or acetaminophen, but it’s definitely better than dextromethorphan.

      I can’t even pretend to believe that last one does anything. Well, I think idiots use it to get high in a scary way.

    • Blaidd@lemm.ee
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      1 year ago

      Guaifenisin is definitely not a garbage drug, it’s very effective for me in ways that prove it works.

      • Ben Hur Horse Race@lemm.ee
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        1 year ago

        what does it do? I honestly dont know, I havent looked it up.

        just to say, you taking it and believing it has an effect is not proof. large, well regulated, double blind studies are proof.

        if you take it and it does something for you thats good and all you need to know, but it aint proof.

        thats reaaaal similar to people who took Ivermectin when they had covid who recovered from covid and say “thats proof Ivermectin cures covid”

        • Blaidd@lemm.ee
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          1 year ago

          It thins out mucus. The fact that it works very well for me is absolutely proof that it works. I started taking it on recommendation from my doctor. Please explain to me how this is at all analagous to people taking horse ivermectin after doctors denied giving them a prescription?

          Edit to add: guaifenisin is the main ingredient in Mucinex, to those who aren’t familiar

          • Ben Hur Horse Race@lemm.ee
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            1 year ago

            lots of doctors gave, and are still giving out ivermeticin on prescription. just the ones who ignore the clinical evidence.

            look I’m not saying it doesnt seem to work for you. I’m saying one person taking any med and seeing results is not “proof”, other than for yourself, but thats really all you need to worry about so it doesnt matter.

            • Blaidd@lemm.ee
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              1 year ago

              Guaifenisin aka Mucinex is an FDA approved drug. Maybe you should look it up since you clearly don’t know anything about it? Or just take the word of a stranger on the Internet who says they went to pharmacy school eight years ago

              • Ben Hur Horse Race@lemm.ee
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                1 year ago

                hey, I wasnt taking anyone’s word for anything. I was only saying one person’s experience isn’t proof, and I stand by that.

                I do owe you an apology though, it was late at night and I misunderstood- I confused guaifenisin with phenylephrine, so we were talking about different things which was totally my fault

          • servermonky@lemmy.today
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            1 year ago

            I take guaifenisn to combat dry sinuses, and it’s helpful there for me. But I’m not sure I’ve seen a difference in on-label use.

            Unfortunately I deal with frequent nosebleeds and sinus headaches from dryness, and there aren’t a lot of options that work well for me

  • SeaJ@lemm.ee
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    1 year ago

    I could have guessed that. Pseudophedrine works great. You just have to ask for it behind the counter because of the whole meth thing.

  • ryannathans@lemmy.fmhy.net
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    1 year ago

    This is not new news, in original studies it never outperformed placebo and has cardiovascular health risks. It’s simply never worked, it’s not a secret, it’s just preferred by governments that your access to pseudoephedrine is limited so this was rushed onto shelves

  • alternative_factor@kbin.social
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    1 year ago

    I got two sinus infections back to back this year and got to learn it the hard way. The doctor was like: “No, you gotta get the REAL stuff!”

    • PetDinosaurs@lemmy.world
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      1 year ago

      I’m with you that it doesn’t work.

      Pseudoephedrine, however, does work.

      Just sign your live away and get the real stuff.

  • DreadPirateShawn@lemmy.blahaj.zone
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    1 year ago

    Not sure why the Lemmy headline says “pill form” – the article says “oral form” does not work.

    So if you’re reading this and wondering about pill vs liquid, then you’re missing the actual message.