Fanny milk, not available in the UK.
I mean it sucks for the horse, but that is a bad-ass photo.
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Abstract
High protein intake is common in western societies and is often promoted as part of a healthy lifestyle; however, amino-acid-mediated mammalian target of rapamycin (mTOR) signalling in macrophages has been implicated in the pathogenesis of ischaemic cardiovascular disease. In a series of clinical studies on male and female participants (NCT03946774 and NCT03994367) that involved graded amounts of protein ingestion together with detailed plasma amino acid analysis and human monocyte/macrophage experiments, we identify leucine as the key activator of mTOR signalling in macrophages. We describe a threshold effect of high protein intake and circulating leucine on monocytes/macrophages wherein only protein in excess of ∼25 g per meal induces mTOR activation and functional effects. By designing specific diets modified in protein and leucine content representative of the intake in the general population, we confirm this threshold effect in mouse models and find ingestion of protein in excess of ∼22% of dietary energy requirements drives atherosclerosis in male mice. These data demonstrate a mechanistic basis for the adverse impact of excessive dietary protein on cardiovascular risk.
Or OneDrive.
File > Save As > Desktop.
Doesn’t save to local Desktop, but the OneDrive desktop wherever the fuck that is.
Drinks are served in jars, and your fries, well, you get 8 fries in a rusty old can.
They called him Fluffy
Fuck the monarchy. Fucking parasites.
Because they are cruel,heartless bastards, whose sole purpose is to make the wealthy more wealthy, achieved primarily by funneling public money into the hands of their like minded mates.
And the menu doesn’t show the price like:
Cheeseburger £13
Instead you get:
Cheeseburger 13
So cool and minimalist.
So you’re saying it’s pronounced helicopter, and not helicopter?
Not just chips my friend. Pies, sausages, chicken, salmon. Half the cooking time or an oven, better results and a fraction of the energy use.
The hype is real.
Ahh, Italian football fans, famous for checks notes overt racism, and stabbing visiting fans.
The brain accessed ROM when it should’ve accessed RAM.
Hypershambles
Mr Cunty