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Joined 1 year ago
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Cake day: June 12th, 2023

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  • I agree with the other reply that pdfs are terrible for e-readers. That being said, Pocketbooks can open them (which is not that common) and it is possible to read them, although it isn’t so comfortable, especially for A4 pdfs. It can also open wide range of other formats and I’m quite happy with it in general. You can connect it to a computer and simply copy your books there, among other means of getting books there. But I have to say I have no first hand experience with competition.





  • There were some compatibility problems that required genetic engineering of the pig. I don’t remember specifics, but there was talk about potential dormant viruses in pig DNA that need to be removed first, possible problems with glycolsylation (sugar chains on the proteins outside of cells) and maybe more. The article also mentions that the pig had some human genes, I’m sure those help compatibility too. So many changes would be next to impossible to do until relatively recently, before use of CRISPR-Cas9. Also, it must’ve taken some time to certify the procedure. That’s why it took so much time since the topic was hot.



  • You don’t need profit in the sense of making lots of extra money compared to how much money you actually put in. I would be very interested in how much net profit is compared to gross in relative numbers. It’s a lot in absolute numbers, but I suspect not so much in relative. The problem why drug development is so very expensive is that you don’t just pay large sums for the drugs that are developed, but also for all those that are not, because they prove not useful during the testing. And there is way, way more than the successful ones, perhaps 100 to 1? I don’t have numers at hand. So in the end, you have to charge a lot of extra money above the production cost if you want to have enough money to develop any drugs at all.

    Of course, that isn’t true for old drugs. Which is a reason why generics are so much cheaper. And also why patents need to exist.

    I’m sure pharma companies abuse the system as much as they can, but not as much as it might appear at a first glance.